Ground water model for Calabar South was developed, based on fourteen parameters (water quality) such as Temperature, PH , Dissolve Oxygen, water quality, TCC, THC, Nitrate concentration, BOD, Conductivity, Turbidity, and Ammonium. The Boreholes were investigated for four months from ten sampling locations. The contaminant compound of interests were total coliform count, heterotrophic count, and nitrate concentration, due to their hazardous nature and health problems to the society. The predicted values were compared with the actual concentration values. The values were retrieved and analyzed in the SPSS Enter model package to find the concentration of Nitrate, THC and TCC in the ground water for various locations. In the entire model, total coliform accounted for 18.429, total heterotrophic count 14.75% with a predicting value of 21.22%. the percentage error between the actual and calculated values was 42.76% and a regression equation of best fit developed as: Y= b0 + b 1X 1 + b 2X 2 + b 3X3 (where Y=Water quality, b o = Regression constant, b 1 - b 3 = b-variates, X 1 - X 3 = Model predictors). The result reveals that about 50% of the parameters considered failed to meet the required objectives. The predictors constant were, TCC, THC and NO 3. Based on the statistical analysis, the predicted model may be expressed as Y = -17.261 + 3.849x 1 +0.861X 2 +1.6E- 12X3.